头孢菌素和青霉素交叉过敏反应的结构基础探讨 Studies on the structural basis of cross anaphylactic reactivity between penicillins and cephalosporins
结论青霉素、阿莫西林及解热镇痛类药物是引起药疹最常见的药物。 Conclusions Penicillins, especially amoxicillin, and NSAIDs are the most frequent causes of drug eruption.
TEM-1、TEM-2对青霉素类有较强水解作用，对第一代头孢菌素和第三代头孢菌素头孢哌酮也有一定程度水解，而对第二代头孢菌素头孢呋新及其它第三代头孢菌素均无水解作用； The penicillins, the first generation cephalosporins and cefoperazone were hydrolyzed by TEM-1 and TEM-2, but TEM-1 and TEM-2 were unable to hydrolyze the second generation cephalosporins cefuroxime and other of the third generation cephalosporins.
结果所诱导的细菌对氟喹诺酮类、头孢类、青霉素类抗生素多重耐药； Results Compared with the parental strains, the mutants were resistant to quinolones, cephalosporins and penicillins;
氨基甙类及青霉素类抗生素在水牛体内代谢动力学的研究 Pharmacokinetics study of aminoglycosides and penicillins antibiotics in buffaloes
结果：排列前三位的药物为青霉素类、喹诺酮类、头孢菌素类； Results: Penicillins, quinolones and cephalosporins were in the first three places;
屎肠球菌对青霉素类抗生素的耐药性与β-内酰胺酶产生率呈正相关。 There is positive relation among S. faecium producing β lactamase and penicillins resistance.
产AmpC酶菌对青霉素类和一至三代头孢类抗菌药物耐药率高达37%～100%； The resistance rate of AmpC enzyme producing strains to penicillins and the first, second and third-generations cephalosporins was 37-100%.
目的：了解青霉素类口服制剂的安全性问题。 Objective: To understand the safety of oral penicillins agents.
几种新的青霉素类及氨基糖甙类药物对尿糖测定的干扰研究 Interference of new penicillins and aminoglycosides with urine glucose monitoring tests
结果30株铜绿假单孢菌中，对β-内酰胺复合物（青霉素类）耐药率为100%，对氯霉素耐药率为90%； Results Among 30 strains of P.aeruginosa, the resistance rate to β-lactam compounds ( penicillins) was 100% and that to chloromycetin was 90%.
在三岁以前，胃酸分泌处于低水平，对酸不稳定的药物，例如青霉素的吸收会增强。 Before then, the stomach has low levels of acid, and acid-labile drugs, such as the penicillins, show enhanced absorption.
青霉素类抗生素在街道环境中耐药菌比例最高； The proportion of penicillins antibiotics in streets was the highest.
LC-MS/MS测定牛奶中六种青霉素类抗生素残留 Residue Analysis of Six Penicillins in Milk by LC-MS/ MS
对大部分其它青霉素类抗菌素，第一、二代头孢菌素及部分第三代头孢菌素有较高耐药性。 Higher drug-resistance to the other penicillins, the first and the second and some third generation cephalosporins.